Layouts
Circular
Circular layouts are mainly used (1) if the displayed sequence itself is circular, (2) to display a non-circular sequence in a space-saving way, and (3) to show interactions between different parts of the sequence(s) using a chord diagram.

17 tools
Linear
Linear layouts are more intuitive and easy to read, but may be extremely long and require zooming and panning.

95 tools
ABrowse

AliView

Alvis

Apollo

BactoGenie

BedSect

CEpBrowser

Cinteny

CNVkit

Combo

Cooler

CRAMER

CRISPResso2

Dalliance

Deep Motif Dashboard

deepTools Heatmap

DNAPlotter

EaSeq

Edgar Genome Browser

Edgar Synteny Plots

EnrichedHeatmap

Ensembl

EpiViz

Galaxy HiCExplorer

GBrowse

GBrowse_syn

Geneious

Genome Annotator Light (GAL)

GenomeView

genoPlotR

GenPlay

Gepard

ggBio

GIVE

Gosling

Gremlin

GView

HiGlass

HiPiler

HUGIn

IGB

Integrative Genomics Viewer

IRScope

Island Viewer

JalView

JBrowse

JuiceBox

Juiceboxjs

Lollipop Plot cBio

MAGI

MEME

MEXPRESS

MGcV

MicroScope

MizBee

MochiView

MSAViewer

my5c

NCBI Genome Viewer

NCBI Sequence Viewer

ngs.plot

Oviz-Bio

Persephone

pLogo

PSU 3D Genome Browser

ReadXplorer

RIdeogram

Sashimi Plot

Savant Genome Browser 2

SCGV

Sequence Bundles

Sequence Surveyor

SilkDB 3.0

Spatial DB

SpliceGrapher

SplicePlot

SpliceSeq

svist4get

SWAV

SynMap2

SynteBase and SynteView

Synteny Explorer

TFmotifView

trackViewer

Two Sample Logo

UCSC Genome Browser

Variant View

VCF Plotein

Vials

Vista Dot

Vista Synteny

VistaPoint

WashU Epigenome Browser

WebLogo

Xena

Space Filling
The space-filling curve is more space efficient than a circular layout and is often used to display a global overview of the genome while maintaining the spatial distribution of features. However, space-filling curves can only show one feature set, and it's hard to visually estimate the distances between two positions in a sequence.

2 tools
Spatial
Spatial layouts display sequences in a 3-dimensional structure.

2 tools