VCF Plotein

https://www.google.com/url?sa=i&url=https%3A%2F%2Fvcfplotein.liigh.unam.mx%2F&psig=AOvVaw3htrc4bxvrx2J7J8ZkHbXp&ust=1605582770728000&source=images&cd=vfe&ved=0CAIQjRxqFwoTCPinlpmMhu0CFQAAAAAdAAAAABAK

Methods

linear single view single scale single focus contiguous no abstraction linear parallel arrangement no interconnection point sparse type

Tool

Access Format web application
Supported Files vcf
License Creative Commons Attribution License
Tool name

VCF Plotein
Tool Link https://vcfplotein.liigh.unam.mx/#/
Documentation https://vcfplotein.liigh.unam.mx/#/

Paper

VCF/Plotein: visualization and prioritization of genomic variants from human exome sequencing projects

Raul Ossio, O Isaac Garcia-Salinas, Diego Said Anaya-Mancilla, Jair S Garcia-Sotelo, Luis A Aguilar, David J Adams, Carla Daniela Robles-Espinoza, VCF/Plotein: visualization and prioritization of genomic variants from human exome sequencing projects, Bioinformatics, Volume 35, Issue 22, 15 November 2019, Pages 4803–4805, https://doi.org/10.1093/bioinformatics/btz458

Abstract

Identifying disease-causing variants from exome sequencing projects remains a challenging task that often requires bioinformatics expertise. Here we describe a user-friendly graphical application that allows medical professionals and bench biologists to prioritize and visualize genetic variants from human exome sequencing data. We have implemented VCF/Plotein, a graphical, fully interactive web application able to display exome sequencing data in VCF format. Gene and variant information is extracted from Ensembl. Cross-referencing with external databases and application-based gene and variant filtering have also been implemented. All data processing is done locally by the user’s CPU to ensure the security of patient data.